Summary: The laryngeal echolocation is regarded as one of the conspicuous traits that play major roles in flourishing bats.Whether the laryngeal echolocation in bats originated once, however, is still controversial.We here address this question by performing molecular Robotics convergence analyses between ancestral branches of bats and toothed whal

Abstract Background There are complex interactions between aging, frailty, diet, and the gut microbiota; modulation of the gut microbiota by diet could lead to healthier aging.The purpose of this study was to test the effect of diets differing in sugar, fat, and fiber content upon the gut microbiota of mice humanized with microbiota from healthy or

Recent advances in integrating microengineering and tissue engineering have enabled the creation of promising microengineered physiological models, known as organ-on-a-chip (OOC), for experimental medicine and pharmaceutical research.OOCs have been used to recapitulate the physiologically critical features of specific human tissues and organs and O

Cyber-physical production systems (CPPS) and digital twins (DT) with a data-driven core enable retrospective analyses of acquired data to achieve a pervasive system understanding and can further support prospective operational management in production systems.Cost pressure and environmental compliances sensitize facility operators for energy and re